Making Schizo Powder (PCMO)

WE'RE MAKING IT INTO THE MENTAL HOSPITAL WITH THIS ONE

Three out of four wall voices agree that PCP is the best.

I think they should invent a kitchen knife that doesnt whisper

The voiceover of you saying: "It wasn't an issue and the condenser kept everything inside" while we can see a column of liquid rising in the liebig condenser was extremely funny. We really like to play down near-misses on accidents.

I absolutely love how this guy casually makes HCN as a biproduct and doesnt bother putting any disclaimer. Btw love your content 😘

We making it on the watchlist with this one🎉🙂‍↕️🗣️❗️

Just seeing 3 rings arranged like that screams “I will fuck you up”

we all are waiting for you to make legal meth analogue

I can still remember watching myself, from the street corner, riding a bike, while riding a bike and watching myself on the street corner..... Don't smoke angel dust, kids..

From an average person's perspective, it simultaneously looks like suffering and like some sort of dark magic. I actually appreciate that you post videos even though it's not a complete success.

You do not expect to see a full Arylcyclohexylamine synth every day on YouTube, good shit

Dissociative substance synthesis in a chemistry youtube channel? We're truly living a eventful decade

Making [REDACTED] powder, only on YouTube!

This is some groundbreaking shit in terms of youtube chemistry, love to see it and also that you explain your mistakes so us chemists can learn from them and not make them ourselves

I’ve never liked people referring to psychedelics or dissociatives as “psychotomimetic.” Veeery early on in their discovery, some scientists did kind of dismissively assume “Oh, LSD is altering your consciousness in this extremely complex & hard to characterize way… This must be what it’s like to experience psychosis!” But this is a profound mischaracterization, which is why (at least for most 5HT2a receptor agonists), it’s largely been dropped as we’ve come to understand both psychotic mental illness AND psychedelics better. The fact that people are still inclined to talk about PCP this way probably has more to do with media sensationalism than anything (though I’ve never done PCP & can’t say for sure)— from what I’ve heard it’s really just more stimulating than other dissociatives & therefore not suitable as a tranquilizer/anaesthetic. Beyond that difference… Like, sure, there are people who freak out & have mishaps on it, & I’m not saying people necessarily should be using it, but people freak out & have mishaps on too high a dose of all kinds of things. That doesn’t necessarily mean it was truly comparable to psychosis. I think psychotomimetic is a perfectly reasonable label for deliriants, & really that they’re the class which should’ve been labeled this way from the beginning… Completely hallucinating whole scenarios/people/conversations/animals/shadow people/etc. that aren’t there; hearing schizophrenia-like voices in your head; extreme fear/paranoia; extreme confusion & disorientation/disconnection from reality… These are the very psychosis-like symptoms of deliriant poisoning, or having intentionally taken Amanita Muscaria mushrooms, or diphenhydramine, or whatever— terrifying, awful, nightmarish stuff which I strongly suspect TRULY comes as close to simulating what a psychotic condition like schizophrenia as any chemical can induce… There’s not much else to it— those are the primary effects. You JUST feel like you’re losing your mind & living in a waking nightmare. On the other hand, dissociatives have considerably more interesting content to them, & far fewer of the truly psychosis-like symptoms. I’ve rarely heard or someone taking ketamine, or MXE, or DXM, or even PCP & legitimately hearing terrifying whispering or screaming in their head for hours they they just couldn’t shake off (whereas I’ve heard of people taking Amanita Muscaria extract 1 time in not that high of a dose & experiencing those kinds of symptoms for DAYS or WEEKS afterwards). You don’t have true hallucinations or dissociatives… You may have beautiful closed eye visuals, but that’s quite different from a nightmarish waking dream state where you literally don’t know what’s real & what’s not. I’d place dissociatives more as a middle-ground, because they do have a tendency to induce some delusions (usually just during the experience, which is why the issues mainly come about in cases of addiction/dependency, where someone is taking them all the time & never getting a breath of air from that state & assessing their experiences from a more lucid, rational perspective). Classical 5HT2a agonist psychedelics, IMO, are the farthest from “psychotomimetic” of any of these. I think it really was just ignorance that led to this labeling for LSD & psilocybin & the like early on; keep in mind that it was being applied so early on that we were only just even learning that serotonin had anything to do with mood/behavior— in the very earliest days of the discovery of LSD & it’s effects. It’s very much a vestige of an impoverished earlier state of psychopharmacological & psychiatric research. The effects induced by psychedelics like these may seem very chaotic & overwhelming, especially to the uninitiated, to someone who didn’t know what they were getting themselves into, or to someone who takes an excessive dose for their first time & plunges in deeper than they’re ready for… But upon the kind of deeper inspection that mystics & shamans have been giving these experiences/states for ages, & the kind that psychedelic scientists & “psychonauts” have more recently devoted themselves to, there’s actually a profound & beautiful order to that chaos; the fact that it’s unpredictable & too complex for our minds to easily put in a box, to reduce & identify with some very simple pattern or experience we’re familiar with, doesn’t mean that it’s actually untethered from reality or random or meaningless or in any way equivalent to symptoms of psychosis. And especially as classical psychedelic doses increase (besides n,n-DMT, which seems to go in exactly the opposite direction), you move towards boundary dissolution & ultimately full ego-death & mystical experience… Which is quite wildly different from any kind of psychosis. There’s really no comparison. If anything I think it romanticizes psychosis to compare it to something as favorable as psychedelic experience. Even in the fringe cases where someone has a predisposition to mental illness & psychedelics catalyzed the precipitation of a psychotic state, the psychosis it precipitates is going to be very different from the psychedelic state itself.

Congrats on 100k!

I dont know why i expected a taste test at the end of this

When I (didn't) do it, I used potassium cyanide to form the nitrile intermediate instead of the sulfate. I'm guessing using morpholine, you have to form the sulfate first? The phenyl grignard reacts directly with the nitrile to give you your product arylcyclohexylamine, if you use piperidine. The first sulfonation step wasn't necessary for that.

Nothing quite like a good dissociative anaesthetic synthesis in the morning to begin an excellent day!!! Cheers for Chemiolis!! and for H Morris <3

I happen to run a shop that has a lot of ex-convicts, and I get to see all their criminal records. Though PCP may not be nearly as prevalent as meth which causes many more problems due to how common it is, PCP easily takes first place for "most likely to cause a violent crime". It's disproportionate, really. Terrible drug.