The effect of dietary cholesterol on blood cholesterol & individual variability | Dr. Tom Dayspring

Published 2022-09-26
Does eating cholesterol raise our blood cholesterol levels? Why does this vary from person to person? How can you test where YOU fall on the spectrum? All your questions on dietary cholesterol answered.

The usual extremes, “cholesterol is poison everyone should eat zero cholesterol" vs “cholesterol is always harmless”.

We cover cholesterol absorption in the intestine, the effect on serum cholesterol, tests of absorption status, and actionable advice to lower risk.

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Animations: Even Topland @toplandmedia

References:
link.springer.com/chapter/10.1007/978-3-030-56514-…
www.sciencedirect.com/science/article/pii/S0022227…
www.ncbi.nlm.nih.gov/pmc/articles/PMC3965667/
www.nejm.org/doi/full/10.1056/NEJMoa1405386
boris.unibe.ch/64847/1/NEJMc1500124.pdf
academic.oup.com/eurheartj/article/41/28/2618/5875…
academic.oup.com/ajcn/article/109/1/7/5266898
onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.13263
www.gastrojournal.org/article/S0016-5085(04)02028-…

Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.

#NutritionMadeSimple #GilCarvalho

0:00 Introduction
2:09 How the body regulates cholesterol levels
3:28 Intestinal absorption
6:17 Esterified vs free cholesterol
13:14 The Niemann-Pick, an intestinal cholesterol gateway
16:46 Individual variability
20:10 What happens to cholesterol after absorption
30:18 The microbiome & cholesterol
31:58 Phytosterols & other supplements
35:48 Testing your cholesterol absorption
40:27 Pharmacological Management
43:45 Recap

All Comments (21)
  • @dpwright32
    Gil, you are doing such an awesome job! You rescued me from the depths of the low carb, “only the small dense ldl are bad”, “grass fed butter is good for you”, etc.. camp. I have devoured your lessons on how to do my own research. While I had no symptoms of heart disease, part of my 2 year journey to good health (260lbs to 160lbs) included getting my own additional lab work done, including a calcium ct scan, which showed a very high score. I’ve researched as many things as possible, and you single handedly got me to understand “don’t trust someone based on their credentials, look at the data…”. Anyway, thank you SO MUCH! I am spreading the word to my friends. And this interview with Dr Tom Dayspring is a MASTERCLASS!
  • @ThePapawhisky
    I assume that most of us watching have some reason to be personally concerned. Here’s my question: if the tests and treatments are understood and ‘available’, why do most of us never get this high level of health support? Instead we’re learning on YouTube what treatments we are not receiving.
  • This is an amazing discussion. Love that this high quality and evidenced based information is now available to the public
  • If I had a biology teacher like this at school chances are I would have become a doctor. Fascinating insights from an extremely intelligent and knowledgeable person who has the ability to explain difficult concepts and science in simple terms. I salute you sir - you are a rare commodity indeed. All I can say is thank the lucky stars we did not have to design the chemical , biological and electrical functioning of the body or we would never have existed. How in the name of everything did this all come to be?
  • @MKstudiovideo
    At first, I played the video with the notion that I already knew everything important about dietary cholesterol and its effect on our cholesterol (since I watched Gil's previous video on this topic). Yet, I learnt a ton of new information. I really hope more people like Tom Dayspring exist who are experts in their domain of interest and who can simply explain such a difficult topic to a lay person. And I really hope you Gil will be able to find another such excellent people who are willing to do those epic interviews with you because it's a huge service for the world. Thank you both!
  • @chainsong9546
    fantastic...I love how, unlike Peter Attia, he just lets the guest talk and doesnt constantly interrupt with anecdotes and digressions. Chapeau!
  • @0ptimal
    So we are kinda gambling by freely eating fat and cholesterol rich foods? If we don't know how our body is behaving with it? I knew there was variability in how food affects people, but it goes much deeper than I thought. Glad YouTube recommended this to me.
  • Regarding individual variability: I was exercising a lot and eating the recommended low fat diet and my body did not have excess fat, but I felt like I was not robust or strong and my cholesterol was going up. My doctor recommended statins. I asked what lifestyle I could do but when he said " eat less fat" I replied that was not possible since I already ate very little fat. He then said I was likely genetically predisposed to why cholesterol. Later, when I switched to a fairly high fat high cholesterol, low carb diet and I told him look. My cholesterol levels are very good and I eat a lot of cholesterol. He said maybe I have genetically predisposition to low cholesterol. I guess that doctor thinks I had successful gene therapy. In my case, I think my low fat diet contributed to a poor lipid profile and the general health recommendations and assumptions of doctors are not correct.
  • @Radjehuty
    I sincerely hope anyone that watches this knows how much of a privilege it is to have this video as a resource. It's such an excellent overview and easy to understand for a concept that has a lot of nuance. It flies in the face of any diet that professes black & white verbage to describe whether dietary cholesterol is good or not. Maybe I'm in the minority, but I love hearing the "it depends" kind of answer. I much prefer precision over easy when it comes to answers about health.
  • Wow. Our bodies are so amazing. We should take a moment and meditate on this wondrous creation and thank it for all it does. I'm serious.
  • @sd200man
    The complexity of our systems is beyond amazing. This has given me a new appreciation for how complex the cholesterol issue is.
  • I've never heard a such a detailed, comprehensive explanation about this subject. It's so information dense that had to rewatch many parts of it to understand it. I feel privileged to be a subscriber to your channel.
  • I will never understand how the human body is so intricately, thoughtfully and beautiful created and people will STILL deny the existence of God.
  • This was one of the best lectures I have ever listen about nutrition. This is what we really can call “nutriton made simple”. Great analogies. His passion reminded me of R. Taylor. I love people who are passionate about their thing and spread good, science based information in a understandable manner 🤩
  • @jimmccall8030
    This is SO HELPFUL. I am a hyper absorber with very high ApoB, high LDL, high HDL and have been eating 3 eggs daily. Going to switch to one whole egg and egg whites. Thank you. I’m reading and watching all of Dr Dayspring that I can find. Also I really appreciated your recent debunking of the saturated fats are fine report
  • @Schatzie301
    What a brilliant explanation. I’ve been studying nutrition for over 50 years and this is the best and most comprehensive discussion I’ve ever seen.
  • @nikkiguerlain
    Oh my gosh! Your guest is the best ever! He’s so animated and genuinely excited and knowledgeable.
  • @Nicksonian
    After this lesson, I don’t understand how higher HDL has gotten the reputation as being good, if high HDL is a sign of hyper-absorption.
  • Outstanding! If we only had more people like him to explain biology in such simple terms, we would all be better educated and equipped to manage our health in a targeted, meaningful and effective way. Kudos to you Gil for bringing his knowledge to the public.
  • @pegatrisedmice
    I don't think you can do much in terms of how digestible your content can be when you're presenting actual facts, because facts tend to be more complex than eat this, do that and you'll be fine. There's also the problem of other influencers crafting their "facts" such that they appeal to most people and confirm what individuals already believe, and that generates more clicks (it's not fat it's sugar type crowd for example). So I'm very happy you took your time to interview someone of such great knowledge and explaining abilities, because I was confused about this topic for a while but this video cleared it up for me in a matter of minutes (to be fair i did zone out ofter the explanation of low and high absorbers because that kinda answered my question but i will definetly revisit this). Thanks