S2 Episode 5: Adjuvant Chemo in Colorectal Cancer: What's Working Now?

Published 2024-08-06
Join Drs Benjamin Schlechter and Jeff Meyerhardt as they discuss the latest breakthroughs in adjuvant chemo for CRC and share their decision-making in real-world scenarios.


Relevant disclosures can be found with the episode show notes on Medscape www.medscape.com/viewarticle/1000093. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.


Resources


Colorectal Cancer: Prevention, Diagnosis, and Therapeutic Options reference.medscape.com/slideshow/colorectal-cancerโ€ฆ


Colon Cancer emedicine.medscape.com/article/277496-overview


Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer pubmed.ncbi.nlm.nih.gov/15175436/


Duration of Adjuvant Chemotherapy for Stage III Colon Cancer pubmed.ncbi.nlm.nih.gov/29590544/


Overall Survival With 3 or 6 Months of Adjuvant Chemotherapy in Italian TOSCA Phase 3 Randomised Trial pubmed.ncbi.nlm.nih.gov/33098997/


3 Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Combination Therapy for Colorectal Cancer (SCOT): An International, Randomised, Phase 3, Non-Inferiority Trial pubmed.ncbi.nlm.nih.gov/29611518/


Randomized Phase III Study of Capecitabine Plus Oxaliplatin Compared With Fluorouracil/Folinic Acid Plus Oxaliplatin as First-Line Therapy for Metastatic Colorectal Cancer pubmed.ncbi.nlm.nih.gov/18421053/


Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials pubmed.ncbi.nlm.nih.gov/36306483/


Impact of Age on the Efficacy of Newer Adjuvant Therapies in Patients With Stage II/III Colon Cancer: Findings From the ACCENT Database pubmed.ncbi.nlm.nih.gov/23733765/


Comparative Effectiveness of Oxaliplatin vs Non-Oxaliplatin-Containing Adjuvant Chemotherapy for Stage III Colon Cancer pubmed.ncbi.nlm.nih.gov/22266473/


Role of Physical Activity and Diet After Colorectal Cancer Diagnosis pubmed.ncbi.nlm.nih.gov/25918293/


Association of Dietary Patterns With Cancer Recurrence and Survival in Patients With Stage III Colon Cancer pubmed.ncbi.nlm.nih.gov/17699009/


Irinotecan Fluorouracil Plus Leucovorin Is Not Superior to Fluorouracil Plus Leucovorin Alone as Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803 pubmed.ncbi.nlm.nih.gov/17687149/


Feasibility and Acceptability of a Physical Activity Tracker and Text Messages to Promote Physical Activity During Chemotherapy for Colorectal Cancer: Pilot Randomized Controlled Trial (Smart Pace II) pubmed.ncbi.nlm.nih.gov/35014958/