Neuroscience - Long-Term Potentiation

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Published 2013-11-06
Long-term potentiation is thought to be the molecular event that contributes to learning. Through synaptic plasticity LTP is established between various neurons, allowing for the learning process to occur. This video explains the molecular underpinnings leading up to LTP including both early and late phase changes. The video begins with the action potential and outlines the various stages required to establish synaptic changes. These synaptic changes lead to the formation of a stronger synapse and ultimately a stored memory within the brain.

This video is licensed under CC BY-NC-ND 4.0
creativecommons.org/licenses/by-nc-nd/4.0/
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Visit Carleton's Neuroscience Department at carleton.ca/neuroscience/ and check out the podcast at mindingthebrainpodcast.com/

All Comments (21)
  • @CoWsGoNeighh
    It's funny to think that by watching this video I learn how memory works, and by doing so, the exact mechanisms that are displayed in this video IS HAPPENING IN MY HIPPOCAMPUS RIGHT NOW AS WE SPEAK, I CAN FEEL THE GROWTH OF NEW SYNAPSES BY THE INFLUX OF CA2+ IN THE POSTSYNAPTIC CA1 CELL. THE ACTION POTENTIALS ARE AT A ALL TIME HIGH RIGHT NOW.
  • @annieslice2268
    How is it that when one person (or three!) explain this it makes absolutely no sense and this makes it seem so super simple! I don't understand how people passed exams without google and youtube!! thank you so much!! xo
  • @stevenk113
    3:26 Well thanks for reminding me while I'm studying for my exam today.
  • @Psnowdog7
    A great deal of long-term depression happened while I was watching this
  • I'm studying this the night before of my exam. I understand I'm screwed.
  • @42MapleTree
    I've watched a lot of videos about neuroscience. A lot are good, some are great, this was magnificent!
  • @Tphransis
    Being able to visualize this helps so much more than just reading and looking at pictures in the textbook. I don't think I'll ever forget this now, thanks !
  • @Urreasteve
    Wow! I can't express how glad I am that I found this video. My book was not able to explain it as clear as this presentation, my understanding of this subject just expanded because of this video. Thanks!
  • @zenzaiL4D
    I'd like to thank all the people involved in making this very informative video. LTP is a rather complex process and you have managed to make a video that explains the phenomenon in a precise way which makes the concept easier to comprehend. Thank you!
  • The person or persons who created this video know exactly what they talk about - if anyone is doing psycho-biology this is a really helpful source since it explains simply - but in depth - what LTP is. For sure I am coming back for more, keep on doing these videos.
  • @bws7532
    AWESOME VIDEO!! excellent explanation and one of the best voice over's I've ever heard! Great voice! And great explanation. Helped me understand it so much better!! Cannot thank you enough for this.
  • @court7694
    Seriously this video was so awesome!!!! It was so helpful to see the representation of the long-term potentiation and hear the very clear explanation of what was happening. Definitely recommending this video to people in my class. Thank you!
  • @DraugSatan
    Brilliant! Dale Purves' "Neuroscience" offers some really in-depth stuff, but generally fails at mashing in small nails with big mallets, which we sometimes need when cramming. Succinct and precise, and gorgeously presented. Kudos!
  • @Bidia280795
    Thank you for your explanation! Made an hour long lecture much more understandable and bearable!!
  • @OilersLBA
    Fantastic video, thank you very much. This hopefully was part of the LTP in my studying and the forming of new AMPA receptors which hopefully will last a long time!
  • @hanihighest
    Wow, this is an amazing video. I when to lecture, read the notes carefully and read the chapter in Neuroscience book and was still not fully understanding this. After the video I understand it fully. Thank you.
  • @daniel88165
    I feel so much better about taking this biopsych final now! Thank you!
  • Just had my neurosciece lecture about long term potentiation and depression this week. I wasn't able to focus in class. Glad I found your video it is super helpful! Love from Sheffield <3
  • @teee488
    Really good video. Excellent animations and commentary. Beautifull!
  • @jaybestemployee
    Great video on the topic! Better if links to videos of related topics are provided to form a playlist of the subject. Keep it up!