Apo A1 & Apo B: How to Measure Your Cardiovascular Risk Using These 2
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Published 2017-11-08
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ABOUT THIS VIDEO:
There are 2 basic differences between LDL and HDL: content and protein type. LDL has 25% or less protein. HDL has 50% or more protein. In addition, the proteins are slightly different. HDL's protein is called A1; the protein in LDL, VLDL, and other large lipoprotein groups is apo B.
Why the prefix "apo"? Apo as a prefix simply means "part of". And lipoproteins are the proteins that our bodies use to safely transport fats, oils, and cholesterol.
Learn more about lipoproteins here: prevmedhealth.com/more-important-than-ldl-the-trig….
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🩺ABOUT DR. BREWER
Dr. Brewer started as an Emergency Doctor. After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine. While there, he went on the run the post-graduate training program (residency) in Preventive Medicine. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, and stroke prevention clinic.
At PrevMed, we focus on heart attack, stroke, and cognitive decline. We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event. Dr. Brewer provides services via telemedicine to individuals all over the world. We find a lot of undiagnosed prediabetes or insulin resistance. Treating unrecognized risk factors like prediabetes allows reduction of risk and prevention of disease.
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All Comments (21)
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I never see Apo A1 or Apo B specified in my blood labs. Does the ordering MD have to specifically order these two? Are they present in the standard cholesterol labs and I'm just missing it? Thanks, Alex
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Oh my God! I speek spanish, I always get confused with the meaning of HDL and LDL, knowing is something very simple for many but for me it was a crazyness. With this video and the image that you put as an example I understand everything. I undestood why one is hight and why other is low .Thank you very much for removing many years of confusion in my mind.
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I’m absolutely delighted with the change in my ratio with your guidance. .51 in March down to .24 this week. I’m very happy! A 52.94% drop into a super low risk category.
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Thank you so much! Great tools to assist patients into taking their labwork, working out their risk factors and making an informed decisions. Many M.D.'s are not informed of these, just look at the lab sheet and do not understand lipid mechanism.
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Thank you so much. So clear, concise and to the point!
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I wish we had a professor like you when I was studying physiology and nutritional biochemistry. Thank you for all you do. You are helping me to become a better RD💖🙏
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THANK YOU DR BREWER THANK YOU FOR THESE VIDEOS
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Thanks Dr Brewer for this video. So glad I came across it. I just received the results of advanced lipid testing and was getting nervous about the high apoB number (133) but when I did the ratio with ApoA, (200) I saw that it was .67 which your chart says puts me at low risk. And this is with a LDL-C of 202. I'll continue my efforts to get it down even more and I haven't ruled out going on a low dose statin.
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You just made my day, Thank you! My Apo B was 110, worked 6 months on lowering now 89 :). Then got Apo A-1 and it's high, I was so upset until watching this video. My current ratio is 0.4 and I will continue working on lowering my App B. Thank you Thank you!
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Excellent video. Very informative. Thank you :)
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GREAT INFORMATION,THANK YOU.
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thanks for a great video.
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Thank you Dr
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Thanks
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Thank you
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Super topic and would like an update please.
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Are these ratios being discussed in the context of association with particular health outcomes? If so, can we make a claim regarding risk, as that implies causation?
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So I am fantastic since my APOA1 is 205, my APOB is 67 and I am also have a very rare mutation that makes me LPA null and the exam confirmed less than 7 mg of LPA.. Now four men of my family have lived to be over 100, but I don't know if this is related.
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I’m actually looking forward to finding out how mine have changed with your guidance.
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My ratio is .6 (101/170), but I don't understand in what sense this is low risk. Does it mean I don't have plaque? I'm 76, and my doc says my risk of a CV event is 26%, and I should be on a statin regardless of the apo ratio. So low risk of exactly what? BTW I found your Pitava. Looks like I would need to order it from Canada. Are you still taking it? Thanks for all you do.
